Bipolar Disorder and Autoimmunity

There are many factors that contribute to bipolar disorder. Among them are genetic, nutritional, life history, and other environmental factors.

Some people with bipolar disorder have high levels of anti-thyroid antibodies (specifically anti-TPO). Thyroid autoimmunity can cause or contribute to bipolar disorder.

Your thyroid levels should be checked regularly and thoroughly, including autoimmune markers. If you have thyroid autoimmunity and bipolar disorder or symptoms thereof, we can take measures to lower inflammation and autoimmunity to improve your mental (and overall) health.


Kupka, R. W., Nolen, W. A., Post, R. M., McElroy, S. L., Altshuler, L. L., Denicoff, K. D., et al. (2002). High rate of autoimmune thyroiditis in bipolar disorder: lack of association with lithium exposure. Biological Psychiatry, 51(4), 305–311.

About Nicholas Hundley, MS, CNS

Nicholas Hundley is a nutritional biochemist and certified nutrition specialist. He is the main author for the MindWhale blog at He practices nutrition and can be found at

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